Angie Baker and Mr Shehata news video on the BBC News website - click here
A woman who suffered 18 miscarriages has given birth to a healthy baby girl named Raiya, thanks to a pioneering technique of diagnosing and treating multiple miscarriages developed at Epsom and St Helier University Hospitals NHS Trust.
Please see the below links for the full story.
Epsom and St Helier NHS
BBC Sussex
Daily Telegraph
Daily Mail online
ParentPages.co.uk
More articles news.Google.co.uk
Please click below to view a newspaper article on Marie and John Wilson, a couple who beat cancer and years of infertility who have had their dream come true after the arrival of their baby girl.
Dr Shehata is proud to announce his new referenced journal publications, please visit our Reseach section, or click here
There has been recently some media attention regarding a new discovery in the field of miscarriages. MIC-1 link with miscarriages and preterm labour has been known since the year 2000. Here is some information which you may find helpful.
Definition of MIC-1
MIC-1: Macrophage inhibitory cytokine 1. A divergent member
of the transforming growth factor beta superfamily. MIC-1 is produced in
the placenta. There are detectable levels of MIC-1 in the blood of the mother
during pregnancy. Low levels of MIC-1 in maternal serum are predictive for
an elevated risk of early pregnancy loss. Also known as placental bone morphogenetic
protein and placental BMP.
A recent study by an Austaralian group (Tong S, Marjono B, Brown DA, Mulvey S, Breit SN, Manuelpillai U, Wallace EM.) in the Lancet 2004 Jan 10;363(9403):129-30, title (Serum concentrations of macrophage inhibitory cytokine 1 (MIC-1) as a predictor of miscarriage.) showed MIC 1 to have immunomodulatory actions favouring fetal viability. They measured serum concentrations of MIC-1 in asymptomatic women at 6-13 weeks' gestation who subsequently miscarried or who had already miscarried. MIC-1 concentrations in the miscarriage cohort (n=100), were a third of those who had ongoing pregnancies (n=197). Multiples of the median for miscarriage was 0.32 (95% CI 0.23-0.32) versus 1.00 (0.93-1.06) for ongoing pregnancies; p<0.0001. Concentrations were just as low 3 weeks before diagnosis as on the day of diagnosis. That MIC 1 serum concentrations seem to be low weeks before miscarriage suggests possible predictive and causative roles, as well as therapeutic potential.
Its our opinion that MIC-1 is a good predictive marker for miscarriage
but does not, at least at this stage, tell us much about how to prevent
or treat a miscarriage.
To view the interview with Dr Shehata please click one of the links below:
Dr Shehata is grateful for the Channel 4 and Cactus TV production of Richard and Judy show for allowing him to use the interview in his website
Tuesday 6th April 2004
http://www.newsletter.co.uk/story/10045
Thursday 1st April 2004
A new theory about the body's immune system could help prevent thousands of women losing babies, writes Margarette Driscoll from the Sunday Times (21st March 2004)
Full article click below.
http://www.timesonline.co.uk/article/0,,2092-1045261,00.html
